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Frontline Plus & Flea and Tick Control
- Adds methoprene to the ingredient in Frontline -
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Summary: Frontline Plus is a very effective, spot-on flea and tick control medication for pets. The "Plus" part refers to the addition of methoprene to the basic formula of Frontline Top Spot. Methoprene, however, is better applied to the "nest" rather than to the pet itself.
Jack DeAngelis, PhD
OSU Ext. Entomologist (ret.)
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What is Frontline Plus?
 Frontline Plus is my second choice for spot-on flea and tick control on both dogs and cats (see Frontline Top Spot for my first choice). Frontline Plus enjoys all of the advantages of Frontline Top Spot including: can be safely used on both cats and dogs, it effectively controls fleas for 90 days and ticks for 30 days, is waterproof, and does not contain permethrin which is toxic to cats.
Frontline Plus, however, adds the insect growth regulator methoprene to the basic ingredient in Frontline Top Spot. I believe methoprene is better applied as a separate treatment (see below). Otherwise, Frontline Plus is an excellent, all-in-one choice.
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| Adult cat flea (1/5"-1/10") moves between the host animal and "nest" (pet bedding, etc.). |
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| Frontline comes in small, measured-dose packets where the amount of liquid is matched to the weight of the animal. Four dosage levels are available for dogs, one level for cats and kittens. Once applied the insecticide quickly spreads over the entire skin providing protection against flea and tick bites for at least a month. Be careful to apply the liquid to the pet's skin not to the coat.
Fipronil, the active ingredient in all Frontline products, is not readily absorbed so there is less chance of side effects compared to systemic flea medications. Package instructions say that monthly applications are allowed; however, unless fleas are frequently re-introduced into the pet's environment, or continuous tick protection is needed, monthly applications probably are not needed. Re-apply when fleas, "flea-dirt" or ticks are found.
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If you live in a region where heartworm has been reported your pets should be protected from this serious, often fatal, parasitic infection. Even though heartworm is transmitted by mosquito bites we believe that systemic heartworm medications are better protection than topically applied mosquito repellents such as K9 Advantix. See the heartworm page for additional information.
Where to purchase Frontline Plus
Frontline products are available without a prescription from your local veterinarian clinic and online. Our online sources are generally much less expensive than clinics. Frontline is sold in 3 and 6 dose packages, in 4 different dosage levels for dogs and puppies, and 3, 6 and 12 dose packages at 1 dosage level for cats and kittens.
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Frontline Plus @ Amazon
We use Amazon as our online retailer. Amazon continuously screens their 3rd party suppliers and only uses those that offer competitive prices and excellent delivery history. Use the links below to find the Frontline product you need. Be sure to check the "More Buying Choices" box on the right side of the Amazon screen for additional, and sometimes cheaper, sources. Links open in a new window.
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Frontline Plus for Dogs & Puppies
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3-Dose Packs
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6-Dose Packs
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Frontline Plus for Cats & Kittens (one dosage for all weights)
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